Amgen

Global ERP Operations Lead, SAP Platform

United States · Remote (country restricted) · Full time

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About the role

Description from the employer’s posting. Check the employer’s page for the current version.

EmployerAmgen
LocationUnited States
Work styleRemote (country restricted)
Employment typeFull time
Employer posted4 Sep 2026

Career Category

Information Systems

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

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Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Global ERP Operations Lead, SAP Platform

What you will do

Let’s do this. Let’s change the world. As Global ERP Operations Lead, you are responsible for the stability, performance and continuous improvement of Amgen’s ERP (SAP) platform. You lead global ERP run operations and ensure that the systems supporting critical business processes operate reliably, securely and compliantly.

You combine deep SAP operational expertise with strong leadership and stakeholder management skills to ensure service excellence and drive continuous improvement across the ERP landscape.

Key Responsibilities:

Lead global ERP run operations for SAP S/4HANA and integrated platforms, ensuring high availability and performance.
Drive operational excellence through effective monitoring, incident, problem and change management.
Establish AI-enabled ERP operations and AIOps capabilities that use operational data and telemetry to improve system resilience, accelerate issue resolution, and optimize operating costs.
Define and manage operational KPIs and SLAs to ensure reliable ERP service delivery.
Ensure ERP platforms meet cybersecurity, GxP, SOX and GDPR compliance requirements.
Strengthen access management, segregation of duties and security patching processes.
Identify opportunities for automation, standardization and modernization across ERP operations.
Use operational metrics and insights to improve system resilience, user experience and cost efficiency.
Lead and develop a global team of internal and partner resources.
Partner closely with Solution Leads, Delivery teams and Infrastructure teams to ensure seamless system lifecycle management.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of relevant experience

Master’s degree and 4 years of experience

Bachelor’s degree and 6 years of experience

Associate’s degree and 10 years of experience

High school diploma / GED and 12 years of experience

Preferred Qualifications:

Roughly 10 years of experience in enterprises and/or consultancy firms.
Proven success leading ERP implementation and/or operations in large, global organizations, ensuring system reliability and operational excellence.
Deep expertise in SAP S/4HANA, SAP BTP and RISE with SAP/non-SAP environments.
Strong experience managing complex system integrations and enterprise-scale SAP landscapes.
Demonstrated ability to lead service delivery and vendor management through KPIs, SLAs and continuous improvement.
Experience implementing automation and operational optimization initiatives within ERP platforms.
Solid understanding of cloud infrastructure (AWS) and enterprise service management tools such as ServiceNow.
Knowledge of ITIL practices and ERP security/compliance frameworks in regulated environments.
Strong leadership, stakeholder management and communication skills.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range

167,720.30USD -226,915.70 USD

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