Danaher
Master Thesis Project: Stability Study for AAV Viral Vectors
Sweden · Work style not stated · Full time
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About the role
Description from the employer’s posting. Check the employer’s page for the current version.
- EmployerDanaher
- LocationSweden
- Work styleWork style not stated
- Employment typeFull time
- Employer posted
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Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology?
At Cytiva, one of Danaher’s 15+ operating companies, our work saves lives—and we’re all united by a shared commitment to innovate for tangible impact.
You’ll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher’s system of continuous improvement, you help turn ideas into impact – innovating at the speed of life
Working at Cytiva means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies.
At Cytiva you will be able to continuously improve yourself and us – working on challenges that truly matter with people that care for each other, our customers, and their patients. Take your next step to an altogether life-changing career.
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What You'll Do:
The aim of this master thesis is to investigate the stability of adeno-associated virus (AAV) viral vectors with regards to their capsid and genome integrity under different storage conditions. Stability will be assessed using a range of orthogonal methods. The team are actively developing purification solutions for AAV, plasmids, and other viral vector entities used in both research and manufacturing. These vectors serve as delivery vehicles for DNA in cell and gene therapy applications. Our goal is to support customers by providing purification products that enable the production of high-purity viral vectors suitable for use as final drug substances. To ensure product quality, we utilize a comprehensive toolbox of analytical methods to assess parameters such as purity, concentration, and impurities. Accurate determination of AAV concentration during the purification process is critical. This thesis project will involve hands-on work of generating viral vector material in a start to finish process. Key is the use of analytical instruments and techniques for characterizing produced AAV material under variant storage conditions.
Who you are
- Education in Molecular Biology/Biology/Biotechnology/Biochemistry/Chemistry in the level of master thesis work (Examensarbete). The thesis work would be 30 hp starting in January 2027.
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Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.
For more information, visit www.danaher.com.
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- Employment typeFull time
- Employer posted
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