ICON

Senior Clinical System Lead

United Kingdom · Work style not stated · Full time

Apply on the employer’s site ↗See how well you match this job

You apply directly with the employer. ROLIVA does not submit applications from this page and is not the employer.

About the role

Description from the employer’s posting. Check the employer’s page for the current version.

EmployerICON
LocationUnited Kingdom
Work styleWork style not stated
Employment typeFull time
Employer posted28 Sep 2026

Senior Clinical System Lead

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

As a Senior Clinical System Lead at ICON, you will play a critical role in the successful delivery of clinical trial systems that support global clinical research programmes. Acting as the lead systems expert across one or more studies, you will oversee the planning, implementation, maitenance, and optimisation of clinical systems, ensuring high-quality, compliant solutions that enable efficient study execution and data collection.

Working closely with sponsors, study teams, and technology partners, you will provide technical and operational leadership throughout the clinical trial lifecycle while driving continuous improvement and best practices across Clinical Systems.

Show full description

What You Will Be Doing

Leading the planning, setup, maintenance, and oversight of clinical systems used within global clinical trials.
Acting as the clinical systems lead for assigned studies, partnering with internal teams, sponsors, and external vendors to ensure successful delivery.
Translating protocol and study requirements into effective clinical system solutions that support data collection, review, and reporting activities.
Providing oversight of system integrations, data flows, and vendor-managed technologies to ensure data quality and operational efficiency.
Identifying risks, managing issues, and communicating project status to key stakeholders throughout the study lifecycle.
Supporting study start-up activities, project meetings, system reviews, and customer interactions.
Reviewing technical documentation, system specifications, and study deliverables to ensure quality and regulatory compliance.
Leading user acceptance testing and quality review activities for system enhancements and implementations.
Mentoring junior team members and contributing to process improvement, innovation, and best practice initiatives.
Supporting business development activities by providing subject matter expertise during proposals and bid defence meetings.

You Will Have

Bachelor's degree in Computer Science, Information Technology, Life Sciences, Health Informatics, Data Science, or a related discipline.
Significant experience within Clinical Data Science, Clinical Systems, Clinical Data Management, or Electronic Data Capture (EDC) environments.
Strong understanding of clinical trial processes, GCP, and regulatory requirements within regulated clinical research environments.
Experience leading the implementation, management, and optimisation of clinical systems across multiple studies or programmes.
Knowledge of clinical data platforms, data flows, integrations, and system validation principles.
Demonstrated project leadership skills with experience managing multiple priorities and stakeholders.

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits may include:

Competitive base salary and performance related incentives
Health and wellbeing programmes including medical, dental, and vision coverage where applicable
Retirement and pension plans
Life assurance and disability coverage
Employee assistance programmes and wellbeing resources
Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.

Visit our careers site to read more about the benefits ICON offers.

Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.

If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.

Are you a current ICON Employee? Please click here to apply

See how well you match this job Apply on the employer’s site ↗

Check your resume against this job Free, no sign-up. Nothing you paste is stored.

Staying safe while you apply

Never pay to apply, interview or accept an offer. ROLIVA never asks you for payment to apply to a job.
Apply only through the official “Apply on the employer’s site” button, on the employer’s own site, and check that a recruiter’s email uses that employer’s own domain rather than a free email address.
Be cautious of an offer made with no real interview, or pressure to decide quickly or share financial details early.

Does something look wrong with this listing? Use “Report broken link” in the role details, or read ROLIVA’s full job-safety guidance ↗.

Preparing for this role with ROLIVA

Check the fit.
Compare the requirements with the experience you have confirmed, including gaps.
Prepare honestly.
Build interview stories and application drafts from your own evidence.
Keep track.
Save the role and record your own application status and follow-ups.

Create a free workspace or log in.