ICON
Senior Principal Scientist (Sr. Research Scientist), Bioanalytical
United States · Work style not stated · Full time
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About the role
Description from the employer’s posting. Check the employer’s page for the current version.
- EmployerICON
- LocationUnited States
- Work styleWork style not stated
- Employment typeFull time
- Employer posted
Senior Research Scientist- Onsite, Lenexa, KS- Full-Time; Flow Cytometry
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
We are excited to be seeking a new Senior Principal Scientist (Sr. Research Scientist) at ICON in Lenexa, Kansas (KS). The Senior Principal Scientist (Sr. Research Scientist) will lead and conduct scientific research aimed at advancing clinical trials and developing innovative therapies. You will manage sponsor programs, shape assay strategies, and provide expertise for new and complex modalities.
We are seeking candidates with proven method development and Spectral Flow Cytometry experience.
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What You Will Do:
The Senior Principal Scientist is responsible for method development and validation for testing preclinical and clinical specimens using flow cytometry, and ligand-binding analytical methods. In addition, you will oversee transfer robust flow cytometry methods for further for bioanalytical testing.
Desired Experience (flow cytometry experience required, ligand binding experience preferred):
Flow cytometry
Experience with Spectral Flow
Panel design
Gating strategy design
Usage of cytometry software (e.g. FACSDiva, FCS express)
Ligand binding assays
ELISA, ECLIA
PK, PD, and immunogenicity
Usage of relevant software (e.g. SoftMax Pro, Watson)
Method Development
Designs and executes experiments for method development
Develops new scientific approaches to method development and communicates these to the global science team
Mentors junior scientists and advises operation on developed methods
Reviews and approves data of other scientists
Communicates with team members and management regarding project status, purpose, scheduling, problems, etc.
Lead communication with clients regarding project status.
Scientific
Maintain knowledge and skill in all techniques where you perform your work.
Provide scientific input to management and BD about new technology investments and lines of service.
Own discussions regarding scientific results with sponsors, together with project manager
Promotes ICON utilizing scientific skills through scientific communication such as external publication of posters and journal articles.
Perform R&D projects
Training of technicians on technical aspects
Mentor and train staff on scientific topics
Quality and Timely Work Execution
Takes initiative in process development and SOP/WI writing
Legible, logical and reproducible documentation of all experimentation
Has a thorough understanding and complies with GLP and other appropriate regulations
Develops rugged and economical assays
Performs data review of other scientist’s work
Sample Analysis and Assay Validation
Provides key assay input to the validation and bioanalysis team(s) to ensure successful execution
Assay troubleshooting
May perform and document maintenance, trouble-shooting and repairs on advanced instrumentation with support of service engineers or other trained supervisory personnel.
Qualifications
Read, write and speak fluent English
Spectral flow cytometry experience
10-15 years of relevant laboratory experience
MS or PhD with applicable research in a relevant scientific field, preferred
Presenter/Publisher in Regulated relevant field, preferred
#LI-KM3
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
- Competitive base salary and performance related incentives
- Health and wellbeing programmes including medical, dental, and vision coverage where applicable
- Retirement and pension plans
- Life assurance and disability coverage
- Employee assistance programmes and wellbeing resources
- Learning and development opportunities through structured training and career pathways
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply
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- USD a year, after annualising126,000–423,000 (40 listings, 15 employers)
At a glance
- Employment typeFull time
- SeniorityLead / Principal
- Employer posted
- Added to ROLIVA
- Last checked